Commentary: Long-Term Opioid Therapy vs. Serial Intraspinal Injections for Low Back Pain
نویسندگان
چکیده
Low back pain (LBP) is a highly prevalent condition with significant health-related morbidity and a detrimental impact on society. There are several non-pharmacologic treatments for chronic LBP including physical therapy, aerobic exercise, and alternative treatments such as acupuncture. There are no studies that directly compare percutaneous spinal interventions to opioid therapy for LBP. It is unclear whether safe and high-quality healthcare will be achieved if the population of patients with chronic pain is steered towards chronic opioid therapy vs. procedural alternatives. More research is needed to elucidate the mechanism of action both of opioids and intraspinal steroid injections in chronic LBP. We argue that the safest and most patient-centered strategy to treat LBP is to maintain the current clinical guidelines until there are evidence-based guidelines to support an alternative treatment algorithm.
منابع مشابه
CASE REPORTS Recurrent Cellulitis Associated with Long-Term Intrathecal Opioid Infusion Therapy: A Case Report and Review of the Literaturepme_854
Background. Lower-limb edema is recognized as an untoward side effect of intrathecal opioid therapy. Cellulitis, an acute, spreading pyogenic inflammation of the dermis and subcutaneous tissue, predisposed by persistent leg edema, can become problematic in patients on intraspinal opioid infusion therapy. Objective. To present a case of recurrent cellulitis in an elderly lady with persistent leg...
متن کاملDoes long-term opioid therapy reduce pain sensitivity of patients with chronic low back pain? Evidence from quantitative sensory testing.
BACKGROUND Long-term opioid treatment has been used extensively in treatment of chronic low back pain (cLBP) in the last decades. However, there are serious limitations to the long-term efficacy of opioids and related side effects. OBJECTIVES In this study we investigated whether long-term opioid treatment changes pain sensitivity of patients with cLBP. STUDY DESIGN A prospective, nonrandom...
متن کاملP01.48. Biomechanical responses to the mechanical characteristics of a spinal manipulation: effect of varying segmental contact site
Purpose Spinal manipulative therapy (SMT) is a common intervention used to treat low-back pain. Some prior investigations report decreased spinal stiffness following SMT; others report no effect. Given that the efficacy of many therapies (e.g. pharmaceuticals, injections) depend on choice of application site and outcome metric (e.g. fasting vs non-fasting blood sugar), potential explanations fo...
متن کاملSystematic review of therapeutic lumbar transforaminal epidural steroid injections.
BACKGROUND Epidural injection of corticosteroids is one of the most commonly used interventions in managing chronic spinal pain. The transforaminal route to the lumbar epidural space for steroid injection has gained rapid and widespread acceptance for the treatment of lumbar and leg pain. However, there are few well-designed randomized, controlled studies to determine the effectiveness of epidu...
متن کاملEvidence of specific cognitive deficits in patients with chronic low back pain under long-term substitution treatment of opioids.
BACKGROUND There is a growing number of patients worldwide being treated with long-term opioids for chronic non-cancer pain, although there is limited evidence for their effectiveness in improving pain and function. Opioid-use related adverse effects, especially in cognitive functioning in these patients, are rarely evaluated. OBJECTIVES The present study investigated the cognitive functions ...
متن کامل